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natima [27]
3 years ago
9

15. A science student claims that a substitution mutation is less likely to affect gene function than an insertion or deletion m

utation. Use logical reasoning and evaluate this claim.
Biology
1 answer:
Nat2105 [25]3 years ago
6 0

Answer: The change in the structure of the genes or change in the DNA sequence is called mutation. The mutations are of different types that are deletion, rearrangement, insertion and others.

Explanation:

Mutation in which the one to several nucleotides get changed at a point is called point mutation. The point mutation can be in the form of deletion, substitution, and insertion. Deletion will involve the removal of nucleotide that involves the change in the sequence of DNA. When the nucleotide is added to the genome it is called insertion. In deletion and insertion the whole sequence of nucleotides from the point of mutation get displaced this affect the codons in the amino acid sequence which is responsible for protein synthesis so the functioning of the body may get affected by such mutations.

In the case of substitution the new nucleotides are added to the DNA sequence and the one which was already present at that place is removed. So, only one amino acid in the sequence will change so the polypeptide structure will not be affected.          

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Template DNA  5' GATTCAGAGA 3'

Complemntary strand    3' CTAAGTCTCT 5'  

5'   GAUUCAGAGA3'  mRNA strand

codes of mRNA GAU, UCA, UAG

Explanation:

5' GATTCAGAGA 3' is the example of DNA strand having the sequence.

The DNA strand is leading strand and is in 5' to 3' direction

the complementary DNA strand is formed in 3'to 5' direction as the strand of 5' to 3' acts as a tempelate for complementary strand.

During replication which is semiconservative a new template is formed by adding the nucleotides to the growing strand.

DNA synthesis always takes place in 5' to 3' direction.

5' GATTCAGAGA 3'

3'  CTAAGTCTCT 5'    Complemntary strand

Transcription is a process in which DNA sequence is transcribed into mRNA which carries codes for amino acids.

 The 5' to 3' strand is called sense strand

3' to 5' strand is called antisense strand. mRNA is transcribed from antisense strand and is a copy of sense strand.

so the transcribed DNA strand as mRNA will be shown as:

3'  CTAAGTCTCT 5'

5'   GAUUCAGAGA3'  mRNA strand

GAU codes for = Aspartate

UCA codes for = serine

GAG code for = glutamate (when due to mutation GAA will become GAG)

A will not code as it is not in triplets.

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