A variety of reasons. The ongoing debate about federal power had tipped to the side of the 'Federalists,' for one thing. But also, and perhaps more importantly, the practical experience of the nation during the War for Independence had demonstrated that, without a stronger federal government, it would risk failing in its 'grand experiment' of republican self-governance.
The Seven Years’ War, a global conflict known in America as the French and Indian War, ends with the signing of the Treaty of Paris by France, Great Britain, and Spain.
The U.S. government openly stated that they would view any European interference in Latin America as "an act of aggression". This was articulated clearly in the Monroe Doctrine, which stated that the US would respond with military force.
Free Trade, along with rights Church of England, fair trial for all/ Habeus corpus