Answer:
Actually, when two oceanic plates collide, the plate that is older, therefore colder and denser, is the one that will sink. In a contest between a dense oceanic plate and a less dense, buoyant continental plate, you know that it's the dense oceanic plate that sinks.
Explanation:
Answer:
TNF-alpha is expressed as a homotrimer that exerts its activities through binding to two types of receptors: TNFR1 and TNFR2, which are transmembrane glycoproteins characterized by having an extracellular domain with 4 cysteine-rich domains (CRD 1-4) , each with 3 cysteinecysteine disulfide bonds.
Explanation:
TNF-alpha (Tumor Necrosis Factor), which has the characteristic of being a paracrine signaling ligand, is a pleiotropic cytokine that functions as a mediator of immune regulation, the inflammatory response and apoptosis in some cell types. Receptors in this family are involved, with some exceptions, in juxtacrine signaling; that is, both the ligand and the receptor are membrane proteins with extracellular domains through which signaling is established. The cellular responses promoted by TNF are initiated by its interaction with two different types of cell receptors, the type I receptor (55 kDa) and the type II receptor (75 kDa). Both types of receptors are part of the TNF receptor family, members of which include Fas antigen (apoptosis inducer, also called Apo-1 or CD95), CD27 (T-cell activation antigen), CD30 (lymphoma marker Hodgkin) and CD40 (B-cell antigen), which share the characteristic of cysteine-rich sequences in their extracellular domains. This family of cytokines generate cellular responses that include differentiation, proliferation, activation of NFκB and cell death, promoting the aggregation of receptor monomers, that is, they have a transmembrane domain that participates in the solubilization of the receptor and a domain of intracellular death that is involved in signal transduction. The binding of TNF to TNF-R1 induces a signaling cascade through its intracellular death domain, which subsequently leads to the activation of complex I (or inflammatory) of NFkB and proceeds to the transcription of anti-apoptotic genes, pro- inflammatory diseases and apoptosis complex II (caspases).
Answer:
Placebo, Is used to describe a substance given in clinical trial that does not contain the drug.
Explanation:
- Clinical trials are done to evaluate the effectiveness of a drug in treating a particular medical symptom or disease.
- In such case a placebo is used as a control in the experiment.
- A placebo contains all the components as the medicine except for the drug that is being tested.
- A placebo is given to one group of patients having the symptoms for which the drug is tested while another group of patients with same symptoms are given the drug.
- If the group that was given the drug show symptoms of cure while the group that was given placebo does not show changes. Then the drug is said to be effective.
Answer:
Plants absorb carbon dioxide,water and sunlight to make their own food,grow and release oxygen through photosynthesis. They're also huge part in keeping our air clean, The carbon becomes part of the plant ; When humans burn fossil fuels, most carbon enters the atmosphere as carbon dioxide.
Explanation:
If i was u i would look it up thats what i would do
