At its peak, the Ming dynasty made China a global superpower, influencing the known world in trade, culture and might. It spanned nearly 300 years, from the fall of the Mongols in 1368 to the ascendancy of the Manchus in 1644.
Yes. If there is no cause there is no effect.
Technological advancements
A church council maybe about 400AD - the same one that decided to suppress the role and importance of Women in the Church... Hope this helps! :)