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B. As the distance between loci increases, some multiple crossovers go undetected such that the relationship between recombination frequency and map distance ceases to be linear.
Explanation:
When calculating recombination frequencies, and hence, map distances, we might notice that these distances are not completely additive. They might vary. <em>For example, let us say that we have three genes, A, B, and C, in that order. </em>We calculated that the <em>distance between A and B equals 5.9</em> MU and that <em>B and C are 19.5 MU apart.</em> According to this, we might say that the <em>total distance between A and C is 25.4 MU (5.9 + 19.5). </em>However, after a<em> two-point calculation between A and C, the value equals 23.7 MU. </em>
The recombination frequency between these two genes located in the extremes and far apart underestimate the actual genetic distances between them because there might occur other crossing-overs that were not detected. This is <em>when calculating the distance between A and C, we probably will not detect the occurrence of a double recombinant between them, and hence, we might sub-estimate the real distance.</em>
The relationship between the actual map distance (number of crossing overs) and the recombination frequency between two loci, is not lineal. The farther apart are the two genes, the worse is the distance estimation.
<span>It began with selective breeding in the ancient times where a population with desirable traits were bred with other population to achieve a desired set of traits. It then continued with the advance in the discovery of bacteria (Escherichia coli) and antibiotics. Then Watson and Crick discovered the structure of DNA. The latest advance being that of gene sequencing and gene editing tools. </span>
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The cell membrane, therefore, has two functions: first, to be a barrier keeping the constituents of the cell in and unwanted substances out and, second, to be a gate allowing transport into the cell of essential nutrients and movement from the cell of waste products.
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Answer:
Science and biology i think
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