Answer:
I think the answer is the first option, more reliable and harder to use.
Explanation:
I think this because technology is expensive and the most reliable thing we have right now so the other options don't make sense.
Metaphase. During metaphase, spindle fibers attach to the centromere of each pair of sister chromatids The sister chromatids line up at the equator, or center, of the cell. The spindle fibers ensure that sister chromatids will separate and go to different daughter cells when the cell divides