It peaked in Europe between 1348 and 1350 and is thought to have been a bubonic plague outbreak caused by Yersinia pestis, a bacterium. It reached the Crimea in 1346 and most likely spread via fleas on black rats that travelled on merchant ships. It soon spread through the Mediterranean and Europe
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William Penn believed strongly that Indians should be treated fairly. He traveled to the interior of the colony and befriended different Native American tribes. He insisted that the Native Americans be paid a fair price for any land that was purchased from them.
The Articles required unanimous consent to any amendment, so all 13 states would need to agree on a change. Given the rivalries between the states, that rule made the Articles impossible to adapt after the war ended with Britain in 1783.