Question

A synonym for mastery might be:

Answer 1

Answer:

A synonym for mastery might be proficiency or comprehension.

Explanation:

Mastery means to have "comprehensive knowledge or skill in a subject or accomplishment. " (Source: Oxford).

Proficiency means to have "a high degree of competence or skill; expertise. " (Source: Oxford).

Comprehension means to have "the action or capability of understanding something. ".

Comprehension may be more mental focused than the connotation of mastery, but it still fits.

Answer 2

Two that immediately come to mind are virtuosity and dexterity.