<span>it has a specific activation site for enzyme attachment</span>
Answer:
Methotrexate inhibits the synthesis of DNA, RNA, and protein synthesis of the cells in the experiment.
Explanation:
Methotrexate competitively inhibits the enzyme dihydrofolate reductase (DHFR) which is involved in the synthesis of tetrahydrofolate from the inactive dihydrofolate. The methotrexate blocks the enzyme by binding to its active site thereby preventing further reaction of the dihydrofolate reductase enzyme and dihydrofolate. Tetrahydrofolate is a useful material for the de novo synthesis of thymidine, a nucleoside. And without thymidine, DNA synthesis is hindered. Methotrexate therefore inhibits the synthesis of DNA, RNA, thymidylates and of course protein synthesis.
Cells produced at the end of telophase II have half as many replicated chromosomes as cells that started the process.<span>Telophase I is the stage double stranded chromosomes arrive at poles of each cell.</span>
Processes that are most important to human life are oxygen, required for cellular respiration, and glucose, a form of sugar that releases energy during cellular respiration.
