Hey there! I'm happy to help!
One reason conquistadors failed to establish colonies is that the Natives kicked them out. Many of the aboriginal people were very powerful and could easily get rid of the conquistadors.
Conquistadors could also run out of resources. Nothing lasts forever, and if they couldn't obtain enough resources while exploring and settling it would be hard to establish a colony easily.
There could also be dangerous things that could hinder the settlements such as wild beasts, natural events, and diseases.
Have a wonderful day! :D
Though the Declaration of Independence is not a binding legal document it did eloquently express the ideals of the new country, one of which was that the people control the government. This principle of<em> limited government</em> was later incorporated into the Constitution.