OBJECTIVES: To analyze the occurrence and types of neoplasias that have developed in patients submitted to orthotopic heart transplantation in the Cardiac Transplantation Program of the Paulista School of Medicine, Federal University of São Paulo.
METHODS: The present study presents an observational analysis of 106 patients submitted to orthotopic heart transplantation from November 1986 to September 2002, who survived for more than 30 days after the procedure. The immunosuppressive regimen consisted of triple therapy with cyclosporin A, azathioprine and corticosteroid. Only two patients received, in addition to triple therapy, the addition of orthoclone OKT-3. The mean follow-up period was 61.4 months. (variation from two months to 192 months).
RESULTS: Twenty-three patients (21.3%) developed neoplasias, of which 56.5% had skin neoplasms, 30.1% had solid tumors and 13.4% had post-transplantation lymphoproliferative disease (PTLD). The mean interval between transplantation and the diagnosis of neoplasia was: skin - 54.9 months, solid tumors - 24.8 months and DLPT - 70.3 months.
CONCLUSIONS: The occurrence of malignant neoplasms was relatively common in the analyzed population. Skin cancer prevailed in relation to other neoplasms and solid tumors were more diagnosed than lymphoproliferative diseases in this series of patients.
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Explanation:
His “white eyes writhing in his face”, “his hanging face”, the blood jolts “gargling from the froth-corrupted lungs” — all are expressive of the tragic situation the soldiers have to face in war. So, imagery is the device the poet has employed in the poem 'Dulce et Decorum Est' to convey his anti-war message.
Answer:
b. It seemed to me as if nothing would or could ever be known.
Explanation:
In the text, the narrator seemed optimistic about learning until this line.
Answer: The answer is "The y-coordinate should be Negative 3 and one-half"
Explanation:
Answer:
imagery, stanzas, symbolism, tiles, theme ,structure, repeat, sound
