Natives lost control of land and independence, expanded population which resulted in famine, cash crops-displaced the food crops, which resulted in famine, natives died of new diseases like smallpox, thousands of people died because of rebellions
In 1830, they took the state of Georgia to court in a case that challenged Georgia's jurisdictional claims directly. In Cherokee Nation v. Georgia, the Cherokees sought an injunction against Georgia's attempts to implement its act of 1828 asserting sovereignty over Cherokee lands.
Create allies and that’s it
South Carolina is the state where the secession crisis started.