Answer:
Change in the hormone levels.
Explanation:
Adrenal medulla is the inner part of the adrenal gland. The adrenal medulla release different hormones and play important role in maintaining the physiology of the body.
The adrenal medulla secretes the epinephrine and nor epinephrine hormone. These hormones prepare the body during the normal condition and in case of fight and flight situation of the body. During injury, the hormone level may gets disturbed.
Thus, the answer is change in the hormone levels.
It is a systemic non-steroidal anti-inflammatory, which means once it's digested and enter's the blood stream it works on the whole body. The inflammation causing the headache will be treated as well as any other inflammation in the body.
