Disease had the most impact as the result of Columbian exchange because due to this exchange deadly diseases spread across all over the world with the travel and migration of people.
Columbian exchange was as exchange of plants, animals, humans, culture, disease, technology and other things to the Africa, America and many other countries. The Columbian exchange had negative as well as positive impact on both the continents.
Impact on Europe:
This exchange benefited the old world with the introduction of "new world crops" such as corn and potatoes. This exchange had negative impact as well. The transmission of epidemics and African people into slavery were some of negative impacts of Columbian exchange.
Impact on America:
The technology helped in advancement in agriculture and food cultivation while the exchange of disease increased the mortality rate among the Americans.
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According to legend, Ancient Rome was founded by the two brothers, and demigods, Romulus and Remus, on 21 April 753 BCE. The legend claims that in an argument over who would rule the city (or, in another version, where the city would be located) Romulus killed Remus and named the city after himself.
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Many English Catholics came to America to escape religious persecution. ... They were unhappy that their children were studying Dutch language and culture, and feared they would forget their English traditions/ to worship freely and not be persecuted by the church.
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Two factors that helped the US shift to an industrial economy during the Gilded Age included the Transcontinental Railroad and the Bessemer process. The Transcontinental Railroad allowed businesses to ship their goods at a very cheap rate to cities all over the US. This helped these industries to grow.