When they ventured onto the mainland, they found an immense landscape that was already home to tens of thousands of American Indians. Conflict between the two groups was frequent, leading to misunderstandings, exploitation, and violence. While their explorations gave Europeans a better understanding of the Americas, the conquistadors who explored the land now known as Texas often failed to find the wealth and resources they were looking for leading the Spanish to focus colonization efforts further south for many years.
Answer: European carry the hidden enemy to the Indians New diseases. Native peoples of America had no immunity to the diseases that European explorers and colonists Brought with them. Diseases such as smallpox, influenza, measles, and even chickenpox proved deadly to American Indians.