Question

Calculate the carboplatin dose for a 60 year old man patient weighing 200 pounds. the patient's serum creatinine is 1.2mg/dL with a target AUC of 6.
a)655mg
b)505mg
c)578 mg
d)530 mg

Answer 1

Given :

Calculate the carboplatin dose for a 60 year old man patient weighing 200 pounds.

The patient's serum creatinine is 1.2mg/dL with a target AUC of 6.

To Find :

The carboplatin dose.

Solution :

Carboplatin dose is given by :

$C.D = AUC\times [\dfrac{(140-age)\times ( weight \ in \ pounds)}{serum \ creatinine(mg/dL)\times7.2\times 2.2}+25]$

Putting all given values in above equation, we get :

$C.D = 6\times [(\dfrac{(140-60)\times ( 200)}{1.2\times72\times 2.2})+25]\\\\C.D =655.05\ mg$

Therefore, the carboplatin dose is 655.05 mg.