Spent is the most negative connotation.
Explanation:
Fatigued is to feel exauhsted.
Weary is lack of sleep, tiredness.
Tired is just a minimal drousy feeling.
And spent is as if your energy was all used up, consumed.
I’m sorry but without the text I can’t answer the question I don’t know what info is there so I can’t answer without a risk
I think it is D) By the end of the story - no one could believe it - the main character was dead