The correct answer to this open question is the following.
Although you did not specify the time in history or any specific context, we are going to assume that you are referring to the US imperialistic role through history.
Being that the case, we can comment on the following.
The foreign policy actions of the United States reflect selfish, imperialist ambitions since the times of President James Polk and the Manifested Destiny. He expanded the US territory acquiring the Mexican northern states after the Mexican-American War.
Since those years, passing through the times of President Monroe and the Monroe Doctrine and President Theodore Roosevelt and his Roosevelt corollary, the United States has always had interventionist purposes as part of its foreign agenda.
Nobody has granted the US the right or role to be the "big brother" who was looking after the interests of the western hemisphere. That is why the US has had many problems throughout history in the Middle East, Latin America, Europe, and other regions.
I don't know directly but here are some notes that can help
Washington choosing diverse thinkers for his cabinet shows his ability to recognize his weakness in understanding politics and recognizing the talent and intellect of others to guide his presidency.
Hamilton at Secretary of Treasury was more effective because he had more influence over the actions Washington took. Washington supported the National Bank and creation of federal currency as suggested by Hamilton. He also shared Hamilton's view of neutrality toward the French and English during their war.
Though Jefferson proved to have an impact. His desires as Secretary of State were not met by Washington. Jefferson wanted to create an alliance with France and assist them in their war against England. In addition he did not support Washington's action against the Whiskey Boys. Ultimately, Jefferson's lack of influence led to him creating an opposing political party to the Federalists.