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The study of the cell cycle focuses on mechanisms that regulate the timing and frequency of DNA duplication and cell division. As a biological concept, the cell cycle is defined as the period between successive divisions of a cell. During this period, the contents of the cell must be accurately replicated. Microscopists had known about cell division for more than one hundred years, but not until the 1950s, through the pioneering work of Alma Howard and Stephen Pelc, did they become aware that DNA replication took place only at a specific phase of the cell cycle and that this phase was clearly separated from mitosis. Howard and Pelc's work in the broad bean, Vicia faba, revealed that the cell goes through many discrete phases before and after cell division. From this understanding, scientists then identified the four characteristic phases of the cell cycle: mitosis (M), gap 1 (G1), DNA synthesis (S), and gap 2 (G2). The study of these phases, the proteins that regulate them, and the complex biochemical interactions that stop or start DNA replication and cell division (cytokinesis) are the primary concerns of cell cycle biologists.
The most significant progress in this research field came with the demonstration that specific protein complexes involving cyclins were critical for regulating the passage of cells through the cell cycle. These early observations came from biological studies of the cells of rapidly dividing fertilized frog eggs as well as mutant yeast cells that could not divide. The observations suggested that regulation of the cell cycle is conserved throughout eukaryotes, which has since proved to be the case. The mechanism of division in bacteria differs from that of eukaryotes, and the control of their cell cycle is also somewhat different, although again it is linked with DNA replication.
Although the cell cycle is a highly integrated process, distinct areas of interest within this field of study have emerged. For instance, many genes and proteins that influence the passage from one phase of the cell cycle to another have been identified. When their expression is altered by mutation or aberrant regulation, they are usually classed as oncogenes. Other proteins act to hold the cell at distinct points in the cycle (checkpoints) and are known as tumor suppressor genes. Apart from those with a clearly regulatory role, many proteins have important functions in other aspects of the cell cycle; one is replication of DNA and organelles, which is a fascinating process that includes its own repair mechanisms and self-editing. Other fields focus primarily on the mechanical processes of cell cleavage into two daughter cells at the end of mitosis and on the condensation and decondensation of chromatin.
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the window was broken by him
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B. Once more I looked up Women, found 'position of and turned to the pages indicated.
Explanation:
Virginia Woolf wrote her now famous extended essay "A Room of One's Own" as a speech for a women's college in the University of Cambridge. In it, she details and describes how women figures are important for the literary world and even the authorship of novels or written works but women aren't allowed or found to do so. Instead, they are 'supposed' to be confined within the four walls of the house and concentrate on maintaining the household issues. Thus, she began writing for the betterment of the women, their inclusion in the same opportunities in the writing scene. Though they may also have the same talent as that of their male counterparts, they are still denied the rights, encouragements and opportunities to be able to write on their own. So, she claims that <em>"a woman must have money and a room of her own if she is to write fiction". </em>Thus, the sentence from the essay that best supports the thought process Woolf employs in conducting her research for the essay is
Once more I looked up Women, found 'position of and turned to the pages indicated.
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The option used to revise this sentence was C. changed to a question, exclamation, or command.
Explanation:
The original sentence, "You should stand up for your rights," is conveying a suggestion. By using "should", the speaker is presenting his opinion, but not in an imperative manner. It's as if he said, "It would be good if you did this. But, whether you do it or not, it is your decision."
The revised sentence, "Stand up for your rights!", is in the imperative mood, meaning it conveys a command, an order. Unlike the original sentence, this one eliminates the suggestion of a course of action. Instead, it urges the listener to do it, to obey. A sentence in the imperative mood does not need to present a subject– it is inferred that it is the second person. It commonly begins directly with the base form of the verb; the exclamation mark is an indicative of urgency.
When it says the whole world is quiet could mean that theres either no one is around or nobody is listening.
Voice meaning maybe this is there time to speak up and talk.