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1: the saying means the world can be a big stage drawing a line from reality and being deceived. Many people on this earth act is if they are in a play. Hiding behind a mask, pretending everything is okay, pretending they are saints but are only a wolf in sheep clothing.
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C. The particles break connections among brain cells.
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One example could be the red hunting hat, which advertises his uniqueness and also gives him a feel of protection. The reason of this isolation seems to be his pains and troubles. He never addresses his own emotions directly, nor does he attempt to discover the source of his troubles.