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Ray Of Light [21]
3 years ago
11

( i need help with this question!!)sickle cell amenia is a mutation that results in irregularly shaped red blood cells.The disea

se is very common in the african american population.Explain how this mutation is BOTH harmful AND beneficial.
Biology
1 answer:
nexus9112 [7]3 years ago
8 0
It is harmful because it cannot carry us much oxygen. It is helpful because it limits the transmission and effects of malaria, which is common in Africa.
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dimaraw [331]

Answer:

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Explanation:

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4 0
4 years ago
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An individual with Huntington disease has two normal parents. What are plausible explanations for this pattern of inheritance? C
Vitek1552 [10]

Answer and Explanation:

The Huntington disease is caused by a mutation in the gene that codifies for the Huntingtin protein (Htt). The mutation produces an altered form of the protein leading to the neuron´s death in certain areas of the brain.

The Huntington disease characterizes for being,

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There are just a few cases all around the world (3% approximately) in which the disease is expressed with no family history. The progenitors are not affected by the mutation. These cases are very rare and are called <u>"de-novo" mutations.</u> A new mutation is spontaneously produced and it is not inherited from any of the parentals. It consists of an increase in the number of CAG repetitions. In a normal person, the number of CAG repetitions is less than 35. When there are 40 or more repetitions it occurs the disease. But when there are between 35 and 39 repetitions, the penetrance of the disease is incomplete. This is a "gray zone". Those alleles that fall in the gray zone are unstable and might produce the HD. Individuals with these unstable alleles have a tendency to increase the number of repetitions from generation to generation until the number reaches 40 repetitions and the person expresses the disease. This <u>usually occurs in the paternal germinal line</u>, as it is particularly unstable in sperm and probably meiosis greatly affects their instability, causing an increase in the number of CAG repeats.

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