Toxic shock syndrome toxin is a super-antigen produced by Staphylococcus aureus bacteria .it causes toxic shock syndrome by stimulating the release of large amount of interleukin-1, interleukin-2 and tumor necrosis factor .
Interleukin-1:
It is a group of 11 cytokines that plays a central role in the regulation of immune and inflammatory responses to infections .
Interleukin-2:
It is a type of cytokine signaling molecule in the immune system .interleukin-2 is apart of the body's natural response to microbial infection and in discriminating self and non self foreign.
tumor necrosis factor :
Tumor necrosis factor is protein superfamily of type 2 transmembrane protein containing tnf homology domain and trimers .these proteins are expressed predominantly by immune cells and they regulate diverse cell functions ,including immune response and inflammation ,but also proliferation, differentiation and embryogenesis.
Staphylococcus aureus:
Staphylococcus aureus is a gram positive pathogen cable of producing a variety of bacterial exotoxin known as super antigens .
Toxic shock syndrome :
Toxic shock syndrome is an acute disease mediated by the production of super-antigenic toxin .it is rare , life threatening complication of certain type of bacterial infections. often it results from toxins produced by staphylococcus aureus bacteria but the condition may also be caused by toxins produced by group a streptococcus bacteria.
Toxic shock syndrome can affect anyone ,including men , older woman, children and postmenopausal women.risk factors of toxic shock syndrome includes skin wounds ,surgery ,and use of tampons and devices such as menstrual cups contraceptive devices ,etc.
Symptoms of toxic shock syndrome toxin:
A sudden high fever,low blood pressure ,vomiting or diarrhea ,rash resembling sunburn ,muscle aches ,redness of eyes ,mouth and throat ,headache and seizures.
Conclusion:
If you have these symptoms of toxic shock syndrome then immediately call your doctor or consult a doctor and take precautions.
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