3 years ago

Is a conduit for the sarcoplasmic reticulum to remove ca2+ from the cytosol?

1 answer:

4 0

No.
The SR is ordinarily involved in intracellular (cytosolic) calcium *release*, not removal.

SERCA pumps help to control cytosolic calcium levels and calcium uptake, or lack thereof when inhibited e.g. by PLB (phospholamban). Proteins calsequestrin, Triadin, and Junctin work at the ryanodine receptors to help to modulate and control cytosolic calcium levels.

Hope this helps!

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