Take a compound microscope for example, the advantage of this common tool is to magnify a smaller object to make it view clearly. However the disadvantage is if you roll up the course adjustment knob too much the lenses will crack and you will have to give up some money.
Answer:
Essentially there is not an answer. There are two different definitions.
A holoenzyme is an enzyme that needs to be together with a cofactor(s), required for activity.
In some cases, enzymes constituted by several subunits (like DNA polymerase 3) are call holoenzyme as well, because it will only perform correctly when all its subunits are present.
