In the following orbital the lone pair on each N atom is present:
N1: sp3,
N2: p,
N3: p,
N4: sp2,
N5: sp2
Sitagliptin is an anti-diabetic drug used to treat type 2 diabetes and is marketed under the brand names Januvia and others. One carbon atom has no pi bonds, while the first nitrogen atom is linked to two hydrogen atoms. It thus possesses sp3 hybridization.
The second nitrogen atom possesses a single pair of electrons and is bound to three other atoms. It is hence sp2 hybridized. The nitrogen atoms in positions 3, 4, and 5 have sp2 hybridization.
The lone pair of nitrogen in the first nitrogen atom is in the sp3 orbital. The second and third nitrogen atoms' only pair of electrons are in p-orbitals. The fourth and fifth nitrogen atoms' lone pair of electrons are in sp2 orbitals.
Here is another question with an answer similar to this about Sitagliptin: brainly.com/question/28275161
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Answer:
Parkinson's disease is a neurological movement disorder. Common symptoms include tremor, slowness of movement, stiff muscles, unsteady walk and balance and coordination problems. There is no cure for the disease.
Explanation:
Flu is primarily treated with rest and fluid intake to allow the body to fight the infection on its own. Paracetamol may help cure the symptoms but NSAIDs should be avoided. An annual vaccine can help prevent the flu and limit its complications.
They help to prevent the disease from occurring. The immune system becomes familiar with the pathogen and learns how to fight it. Its the same process with vaccines
Answer:
c. Benzisoxazole increases serotonin levels, while amoxapine decreases serotoonin levels