According to a Plimoth Plantation timeline, the Mayflower arrived at Plymouth Harbor on December 16, 1620. The Pilgrims settled in an area that was once Patuxet, a Wampanoag village abandoned four years prior after a deadly outbreak of a plague, brought by European traders who first appeared in the area in 1616
As the final amendment in the Bill of Rights, the 10th Amendment originally aimed to reassure Anti-Federalists by further defining the balance of power between the national government and those of the individual states