This is a long question please rephrase it.
Founded in 1836 by Dr. Marcus Whitman<span> and his wife, Narcissa, the </span>Whitman Mission<span> was the site of one of the worst tragedies along the Oregon Trail. The Whitmans, Methodist missionaries, offered religious instruction and medical services to the local Cayuse Indians.</span>
Constantinople (known today as Istambul). It sits on the Bosphorus Strait, a waterway that separates Asia from Europe.