Biochemistry involves the production and degradation of biological molecules such as nucleic acids, proteins, lipids, carbohydra
tes, and vitamins. Changes in the production or degradation of these important molecules can cause disorders and diseases in humans. For each of the human disorders and diseases listed below, indicate whether it is caused by a change in: (A) nucleic acids (for example: DNA or RNA); (B) amino acids/proteins; (C) lipids (for example: cholesterol or triglycerides); (D) carbohydrates/sugars; or (E) vitamins. Provide only one (1) answer for each disease.
Degradation of nucleic acids causes Lesch-Nyhan syndrome and mitochondrial depletion syndromes in human body, degradation of proteins causes phenylketonuria and tyrosinemia diseases in humans, degradation of lipids causes Gaucher disease and Tay-Sachs disease. Due to these diseases of lipids, we have not enough enzymes to break down lipids, degradation of carbohydrates leads to diabetic ketoacidosis, hyperosmolar coma and hypoglycemia, and degradation of vitamins causes anemia and scurvy diseases in the body.
