The answers are A) D) and B).
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He made hundreds of appointments, of which not all were delivered by Jefferson's Secretary of State James Madison, leading to Marbury v. Madison.
The scientific method changed the way scientists worked in the 16th century in several different ways. However, one of the most important ones was the fact that it forced scientists to rely on observation and experimentation in order to support their conclusions. This led to many discoveries and scientific advancements, as scientists got closer to the reality of the natural world. It also decreased the influence that tradition and dogma had on science.
The primarily responsible for the cold war was USA