The most signficant impact of the anti-federalists on the Constitution was the implementation of the Bill of Rights.
Anti-federalists were concerned that the new US Constitution gave too much power to the federal government. Anti-federalists argued that a strong central (aka federal) government would result in tyranny, just like it did when America was still part of the British empire. This is why the anti-federalists wanted a list of rights that all American citizens can possess. This list of rights would check the power of the federal government and prevent the government from restricting the rights of citizens.
OK so basically the answer will be that it provided many new different ideas to the American colonists.
I know number, one which is
B
The biggest issue is by technology.
The American people had a voice and the amendments allowed people to vote. Like the 13, 14, and 15 amendment allowed all people to vote. Their voice could get heard