Answer:
Something that's done manually is done by hand, rather than by machine. The opposite of this is when something's done automatically, by machine or some automated system.
Explanation:
self-acting, semiautomatic, self-activating, machine-driven, self-moving, automated, machine-controlled, self-locking, self-regulating, autoloading, white-collar, self-winding, smart, self-loading, automatic.
I'm pretty sure those are all the antonyms and synonyms of the word.
