Answer:
Which of the following is not an effect of meiosis?
Causes more genetic diversity in sexually
Explanation:
Answer:
Explanation:
Pharmacophore (pharmacology) - The molecular framework responsible for a drug's biological activity. According to IUPAC — A pharmacophore is the ensemble of steric and electronic features that is necessary to ensure the optimal supramolecular interactions with a specific biological target structure and to trigger (or to block) its biological response.
Privileged structures are defined as molecular frameworks which are able of providing useful ligands for more than one type of receptor or enzyme target by judicious structural modifications.
1) The 1,4-dihydropyridine ring is present in many biologically important molecules that acts as an important scaffold for cardiovascular drug - a calcium antagonists and although it is technically not considered as a pharmacophore, it is considered as a privileged structure.
1,4-Dihydropyridine (DHP), belongs to the class of calcium antagonist that inhibits the influx of extracellular Ca+2 through the L-type voltage-dependent calcium channels.
A positional substitution in the 4-position is feasible in the heterocyclic ring which in turn culminates in various calcium channel antagonist activities and this heterocyclic ring is the common feature for various pharmacological activities such as anti-inflammatory activity, analgesic activity,
antihypertensive, antianginal, antitumor, antitubercular activity and antithrombotic .
Position on the heterocyclic ring binds to the L-type channel and also to N-type channel on membranes.
2.) The bioisosteres are not a suitable bioisostere for the traditional C-4 aryl or heteroaryl substitution which is necessary for calcium ion blockage thereby inhibiting it to function with the mechanism shared above.
At short focusing distances, ciliary muscles contract causing the suspensory ligaments to tighten.
The ciliary muscle is an integral muscle of the eye that is constructed as a ring of smooth muscle in the middle layer of the eye, the uvea (vascular layer). It regulates the passage of aqueous humor into Schlemm's canal and governs accommodation for observing objects at different distances.
A suspensory ligament is a ligament that provides support to a body part, particularly an organ. The suspensory ligament protects the fetlock from hyperextension (i.e., falling too low) during exercise. The ligament begins in both the fore and hindlimbs at its connection to the back of the upper cannon bone.
When the ciliary muscle relaxes, its diameter increases; when the suspensory ligaments tighten, the lens becomes thinner. This occurs when concentrating on a celestial object. When the ciliary muscle contracts, the lens becomes much more circular and has more focusing power because the pressure on the zonular fibers is reduced. When the ciliary muscles relax, these fibers contract, pulling the lens out and creating a flatter shape with less focusing power
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Terms matched with the right definitions.
1. An organism that can make its own food – Autotroph
2. A symbiotic relationship between two organisms in which one species benefits and no effect is apparent to the other species – Commensalism.
3. A cell that has a membrane-bound nucleus and/or organelles as its major characteristic -Eukaryote.
4. The study of organisms that are too small to be seen with the naked eye - Microbiology.
5. A disease-causing organism - A germ pathogen.
6. A one- or few-celled organism with chromosomes; may have characteristics of both animals and plants – Protist.
An autotroph is an organism that produces its own food from simple substances available in its environment. Autotrophs usually use inorganic chemical reactions or light energy in producing their food and are usually the producers in a food chain. Examples of autotrophs are plants and algae.
Commensalism is a type of relationship between organisms of two species where one organism benefits from the relationship and the other organism is not affected by it (neither benefits nor harmed).
Answer:
Answer is E.
Explanation:
Chromosomal inversion is a situation involving the segment of a chromosome where it is turned upside down and reinserted back into the chromosome. This usually occurs because of a breakage and rearrangement occurring within a single chromosome.
It is of a two types, these are
* Paracentric chromosomal inversion - a type where a segment not including the centromere is snipped out, inverted, and inserted back to its location on chromosome.
* Pericentric chromosomal inversion - is a type where a segment including the centromere is snipped out, inverted, and inserted back to its original location on chromosome.
