Question

DNA has two strands. If the sequence of nucleotides of one strand was known, is it possible to use that information to determine the sequence of the second strand? Explain your reasoning for your response using an example DNA sequence of at least 10 nucleotides with no consecutive letters that are the same.

Answer 1

It is possible to use the information of the nucleotide sequence of one strand to determine the sequence of the other strand.

• Deoxyribonucleic acid (DNA) is a biological molecule with two strands. Each strand is made up of a sequence of nucleotides. The DNA nucleotides are Adenine (A), Cytosine (C), Guanine (G) and Thymine (T).

• In a DNA molecule, Adenine forms an hydrogen bond with Thymine i.e. A-T, while Guanine forms an hydrogen bond with Cytosine i.e. G-C.

• Therefore, it is possible to use the information of the nucleotide sequence of one strand to determine the sequence of the other strand. For example, a strand with ATGCGTACGAT will form the following sequence: TACGCATGCTA

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