The most significant limitation to the clinical utility of anthracycline antineoplastic medicines, which include doxorubicin (adriamycin), daunorubicin, or epirubicin, is the danger of cardiotoxicity.
- Nevertheless, these substances continue to rank among the most popular anticancer medications.
- Although the oxidative stress-based concept involving intramyocardial formation of reactive oxygen species (ROS) has acquired the most respect, the molecular etiology of anthracycline cardiotoxicity is still quite debatable.
- Through redox cycling of both their aglycones and anthracycline-iron complexes, anthracyclines may facilitate the generation of ROS.
- Given the remarkable cardioprotective efficacy of dexrazoxane, this suggested mechanism has gained a lot of traction (ICRF-187).
What is Influenza?
- It affects the lungs, nose, and throat.
- High-risk groups include young children, elderly individuals, pregnant women, persons with chronic illnesses, and those with weakened immune systems.
- Fever, chills, muscle pains, cough, congestion, runny nose, headaches, and exhaustion are some of the symptoms.
- Rest and fluids are the main treatments for the flu because they allow the body to fight the illness on its own.
- Anti-inflammatory painkillers sold over-the-counter may aid with symptoms. An yearly flu shot can lessen complications and aid in prevention.
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<span>Since alkylating agents work to prevent the cell from replicating its genetic material, the cell would most likely stop at the interphase checkpoint, which is the phase before mitosis (which consists of prophase, metaphase, anaphase, and telophase). During interphase, the cell replicates its genetic material (DNA), but this would be prohibited by alkylating agents.</span>
Scratching insect bites can lead to infection, a superficial crusty infection of the skin.The scratching cause the skin around the bitten area to break open which causes infection. Example of insect that bites are mosquito, midge and flea among others.
A physical property is any property that can be measured without changing the composition of matter. Physical properties are used to observe and describe matter.
<span>Protists can be unicellular, colonial or multicellular. Each type of protist has its own phylums or divisions. Protozoans are animal-like. Bacteria and other one-celled organisms are typical prey for a protozoa. Some examples of a protozoa are mosquitoes and amoeba. Algae are photosynthetic and are grouped into divisions depending on pigment similarities. A few examples of algae are sea lettuce and kelp. Fungus-like protists are often brightly colored and get their nutrition by absorbing nutrients from their environment.</span>