A prefix is usually added directly to the base word but there several case where a hyphen is needed.
1. He is in his couch at HOME on the Fourth of July. His home and the couch is the setting
A man's lack of instinct.
Also by studies.
1. Dr. Martin Luther King Jr.: "I Have a Dream" Speech. ...
2. Charles Dickens: A Tale of Two Cities. .
Hopefully this is what you were looking for :).
D. when it tries to sell you products related to your obvious interests