Minor reforms he introduced early in his reign so angered the nobility and clergy that his mother decided in 1765 to come out of retirement and force co-regency upon her son. ... Because the prerogatives of the clergy and minor nobility were unchecked, Joseph remained unsatisfied.
By 1790, Joseph faced numerous problems in his empire, including a loss of control in the Austrian Netherlands. In a weakened state after being ill for years, Joseph made the painful decision to undo his reforms in Hungary in order to maintain the empire's power there.
The first people to do so were the Akkadian's king Sargon (reigned 2334–2284 BCE). He conquered the cities of Sumer and brought them under one system of government.
Na/K concentration in and out of the cell at the homeostatic level. It does this by pumping sodium and potassium ions in and out when it's needed of it in order to maintain the concentration of both ions stable across time.
