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Elis [28]
2 years ago
15

How do prions make more of themselves?

Biology
2 answers:
Nataly [62]2 years ago
7 0

Answer:

problems actually start when some of the prion proteins get misfolded into a form that aggregates (the infectious form), which also induces misfolding in the native protein, increasing the amount of aggregates, and inducing more and more of the native form to misfold.

Explanation:

Mashutka [201]2 years ago
5 0
The problem begins when some of the prion proteins are misfolded into an infectious form, which causes misfolding in the native protein, increasing the amount of aggregates and causing more and more of the native form to misfold.

brainiest pls?
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What are three methods of handling solid waste?
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Explanation:

Methods of Solid Waste Disposal and Management:

Solid Waste Open Burning.

Sea dumping process.

Solid wastes sanitary landfills.

Incineration method.

Composting process.

Disposal by Ploughing into the fields.

Disposal by hog feeding.

Salvaging procedure.

3 0
3 years ago
Cystic fibrosis (CF) is one of most common recessive disorders among Caucasians it affects 1 in 1,700 newborns. What is the expe
Phantasy [73]

Answer: The expected frequency of carriers is P(Aa)=0.046.

The proportion of childs with CF is P(aa)=0.024.

25% of having a child with CF (aa).

Explanation:

Hardy-Weinberg's principle states that in a large enough population, in which mating occurs randomly and which is not subject to mutation, selection or migration, gene and genotype frequencies remain constant from one generation to the next one, once a state of equilibrium has been reached which in autosomal loci is reached after one generation. So, a population is said to be in balance when the alleles in polymorphic systems maintain their frequency in the population over generations.

Given the gene allele frequencies in the gene pool of a population, it is possible to calculate the expected frequencies of the progeny's genotypes and phenotypes. <u>If P = percentage of the allele A (dominant) and q = percentage of the allele a (recessive)</u>, the checkerboard method can be used to produce all possible random combinations of these gametes.

Note that p + q = 1, that is, the percentages of gametes A and a must equal 100% to include all gametes in the gene pool.

The genotypic frequencies added together should also equal 1 or 100%, and all the equations can be summarized as follows:

p+q=1\\(p+q)^{2}  = p^{2} +2pq+q^{2} = 1\\P(AA)=p^{2} \\P(aa)=q^{2} \\P(Aa)=2pq1

So, there are 1700 individuals and only one is affected. Since it is a recessive disorder, the genotype of that individual must be aa. So the genotypic frequency of aa is 1/1700=0.000588.

Then, P(aa)=q^{2}=0.000588. And with that we can calculate the value of q,

P(a)=q=\sqrt{0.000588}=0.024

And since we know that p+q=1, we can find out the value of p.

p+0.024=1\\1-0.024=p\\p=0.976

Next, we find out the genotypic frequency of the genotype AA:

P(A)=p=0.976\\P(AA)=p^{2} = 0.976^{2}=0.95

Now, we can find out the genotypic frequency of the genotype Aa:

P(Aa)=2pq=2 x 0.976 x 0.024 = 0.046

Notice than:

p^{2} + 2pq + q^{2} = 1\\x^{2} 0.976^{2} + 2 x 0.976 x 0.024 + 0.024^{2} = 1

Then, the expected frequency of carriers is P(Aa)=0.046

The proportion of childs with CF is P(aa)=0.024

If two parents are carriers, then their genotypes are Aa.

Gametes produced by them can only have one allele of the gene. So they can either produce A gametes, or a gametes.

In the punnett square, we can see that there genotypic ratio is 2:1:1 and the phenotypic ratio is 3:1. So, there is a probability of 25% of having an unaffected child, with both normal alleles (AA); 50% of having a carrier child (Aa) and 25% (0.25) of having a child with CF (aa).

5 0
3 years ago
In which stage of cell division is the dna copied?
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Mitosis in the stage prophase chromosome and DNA is copied
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ehidna [41]

Answer:

Lysosome - Janitor, cleans up food particles, waste, and dead cell parts.

Nucleus - Principal, contains DNA and is the control center for the cell.

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Hope this helps!

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2 years ago
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