English queen Mary, known also as Bloody Mary died from ovarian cancer.
Explanation:
During her marriage, she suffered from a false pregnancy syndrome and was abandoned by her husband, thus becoming a more tragic person than a tyrant, described by many historians.
She had two false pregnancies. Before her death, she made a will, stating that her husband Philip would be regent to their child until he was of age, but ultimately no child was born from her marriage to the King of Spain.
She died on November 17, 1558, most likely from ovarian cancer, and because she did not have the much-desired child, she was succeeded by her half-sister, Elizabeth I.