Emperor Constantine was important because he made many reforms for the empire financially, in the military and socially. He also made the capital Constantinople in present day Turkey. This then became the capital of the Byzantine empire for many years to come He solidified eastern roman power essentially creating the Byzantine empire.
Originally humans simply hunted and gathered, but this nomadic lifestyle made having a large family difficult and culture was therefore rarely passed on.
The Black Death is widely believed to have been the result of plague, caused by infection with the bacterium Yersinia pestis. Modern genetic analyses indicate that the strain of Y. pestis introduced during the Black Death is ancestral to all extant circulating Y. pestis strains known to cause disease in humans. Hence, the origin of modern plague epidemics lies in the medieval period. Other scientific evidence has indicated that the Black Death may have been viral in origin. (britannica.com)
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They wanted to gain power over their neighbors and also to oust American and European influences from the region. Early in 1941, the western powers were beginning to pay attention to the situation. America sent troops to the Philippines.