The hypothesis by Coleman was that the product of the ob+ gene was the appetite suppressing hormone. Hence, the homozygous ob/ob mutant are in a position to synthesize that hormone, and its circulating level would be zero. He also hypothesized that the product of the db+ gene was the receptor for the appetite-suppressing hormone. Thus, the homozygous db/db mutant would be able to synthesize the hormone but would not be in a position to respond to it. It would eat excessively and produce large amounts of body fat, which in turn would produce large amounts of appetite-suppressing hormone . In the absence of a receptor, the db/db mutant's hormone level would remain abnormally high.
Coleman's hypothesis were confirmed when the precise functions of the ob+ and db+ genes were determined. The peptide hormone encoded by the ob+ gene was named Leptin.
Answer: A (catabolism and Anabolism)
Explanation:
Metabolic pathway are basically divided into two categories.
1. Catabolic
2. Anabolic
Catabolic (degradation) pathways, where energy rich complex macramolecules are degraded into smaller molecules. Energy released during this is trapped as chemical energy, usually as ATP.
Anabolic (biosynthesis) pathways. The cells synthesize complex molecules from simple precursors. This needs energy.
A non scientific question is a question which cannot be proved to be true as no experiment or no data can be gathered from it. Why are roses the best flowers? is an example of nonscientific question. The answer of this question is subjective and it brings no scientific data. Scientific question on the other hand is a question that may lead to a hypothesis and help us in answering (or figuring out) the reason for some observation.
Answer
The arm and base of microscope are connected with each other with help of inclination joint. which provide easiness to user during research analysis or other microscopic studies.
It has significant role in light and compound microscope that need light for visualization of examine sample. It also help in easy rotation during focusing toward light for better contrast.
Answer:
deserts
Desert biomes are the driest of all the biomes. In fact, the most important characteristic of a desert is that it receives very little rainfall. Most deserts receive less than 300 mm a year compared to rainforests, which receive over 2,000 mm.
Explanation:
