changes to the mutation is harmful
mutations are basic input of a organism
so playing with mutations is like inviting danger
it will give beneficial and neutral defects to the organism and may take life of it.
the biggest example is playing with virus which caused corona
so you have to compare them to find it
-4/3 is smallest because it is negative
1/3 would come next because it is smaller then the other two
1/2 is smaller than 2/3
and 2/3 is the largest
D. they are all goals of sustainable design