Background- In patients with intracranial artery stenosis, a long-term advantage of dual antiplatelet therapy (DAPT) over single antiplatelet therapy (SAPT) for the prevention of recurrent stroke has not been proven. We studied patients with intracranial arterial stenosis who were enrolled in the Cilostazol Stroke Prevention Study for Antiplatelet Combination trial, a randomized controlled trial in high-risk Japanese patients with ischemic stroke, to compare the efficacy and safety of DAPT with cilostazol and clopidogrel or aspirin to those of SAPT with clopidogrel or aspirin. Techniques and Outcomes In patients with ischemic stroke with symptomatic or asymptomatic intracranial arterial stenosis of at least 50% in a major intracranial artery, we compared the vascular and hemorrhagic events between DAPT and SAPT.
Patients were divided into two groups: 275 were given DAPT, while 272 were given SAPT. In contrast to SAPT, which had a higher risk of serious or life-threatening bleeding, DAPT had a lower risk of ischemic stroke (hazard ratio [HR], 0.47; 95% CI, 0.23-0.95); and a composite of stroke, myocardial infarction, and vascular mortality (HR, 0.48; 95% CI, 0.26-0.91). Conclusions In patients with intracranial artery stenosis following stroke, DAPT using cilostazol was superior than SAPT using clopidogrel or aspirin for the prevention of recurrent stroke and vascular events without raising bleeding risk.
<h3>What is
stroke?</h3>
When anything prevents blood flow to a portion of the brain or when a blood artery in the brain bursts, a stroke, also known as a brain attack, happens. The brain either ages or suffers harm in both scenarios. A stroke may result in permanent brain damage, chronic disability, or even fatality.
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Answer:
It is the cardiac output.
Explanation:
Heart rate x stroke volume = cardiac output.
The cardiac output is the final outcome of all factors that influentiate the ventricular activity (heart rate, heart contractility, and the phenomenon of precharge and postcharge).
Mrs. Maryam a 74-year-old woman who lives alone, is admitted to the hospital because of weakness and confusion. The etiology of the primary imbalance Potassium depletion may be caused by a variety of drugs, including diuretics and heart failure medications. and the body compensating for this imbalance.
This is further explained below.
<h3>What is etiology?</h3>
Generally, etiology is simply defined as the combination of causes, or way of origination of an ailment.
In conclusion, potassium supplements should be administered to the patient. For the time being, diuretics may be avoided.
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Answer:
abnormal amounts of the growth hormone can lead to developmental issues
Explanation:
