The correct answer is - A famine in Ireland prompts US response.
With the Irish famine of the 19th century, and the response to it by the United States, we have a very nice example of domestic influence on foreign policy.
Namely, the Irish potato famine was so bad, that very large percentage of the Irish population actually died, and the rest of the population was on the verge of starvation. Because of this, lots of people wanted to move out of the country in order to at least be able to have food on the table. This prompted a response from the United States, and they made an exception in their strict foreign policy because of the Irish people, so opened their borders to them in order to help them, thus letting them settle in the country.
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Smallpox has had a major impact on world history, not least because indigenous populations of regions where smallpox was non-native, such as the Americas and Australia, were rapidly decimated and weakened by smallpox. During the 18th century the disease killed an estimated 400,000 Europeans each year, including five reigning monarchs, and was responsible for a third of all blindness. After successful vaccination campaigns throughout the 19th and 20th centuries, the WHO certified the global eradication of smallpox in December 1979. Smallpox is one of two infectious diseases to have been eradicated.
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Minerals can not be made of organic materials