I'd just say you should have a good time, enjoy the vacation and think of it as a break. But for the most part, do not stress about school or work on the last day before leaving the vacation area. If you do that, then you'll become groggy for quite a while.
In Tennessee William's play A Streetcar Named Desire, Blanche tells her sister those words and the theme of the play that those lines reflect are "a woman's dependence on men."