Since the Pitx1 gene codes for a protein crucial im lower limns development, a mutation occurring near Pitx1 gene will affect refikjs around the lower limbs but not those far away from it.
<h3>What are mutations?</h3>
Mutations refers to alterations or error that occur which change the original sequence of nucleotides in a DNA molecule.
The Pitx1 gene is a gene that codes for a protein that involved in development of the lower limbs.
A mutation near but outside of the coding region of Pitx1 may cause a loss of pelvic fins without pleiotropic effects on the pituitary gland and jaw because the pelvic fins form part of the lower limbs whole the jaws and the pituitary gland are not found in the lower limbs.
Therefore, the mutation occurring near Pitx1 gene will affect regions around the lower limbs but not those far away from it.
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