There were several important factors that contributed to the ability of europeans to conquer the aztecs and inca, but the most important three were that the Europeans brought guns, germs, and steel weapons.
During the Haitian occupation from 1822 to 1844 it was officially designated as Saint-Yague. Founded in 1495 during the first wave of European settlement in the New World, the city is the "first Santiago of the Americas".