2 The priority is pain management; severe pain requires analgesics. Increased hydration is necessary to promote hemodilution, improve circulation, and prevent more sickling. Cold will constrict blood vessels, further depleting oxygenation to affected parts; warmth is preferable. There is too much swelling and pain in the joints during a crisis for the implementation of range-of-motion exercises.
The main motor cortex (found in the precentral gyrus) and the premotor cortex, which starts and governs voluntary movement, are situated mostly in the frontal lobe, prior to the central sulcus.
