<span>The sentence beginning "There is within me (and with sadness I have watched it in others)..." is your answer. It shows that even though he loved Doodle, he did some things he regrets. He even sees this type of meanness in others and it makes him sad, which hints at his regret.</span>
I would put that he answer is D. Because if he is writing about cuisine, then the best way to figure out the answer is to ask someone who knows about it.
The primary setting of "Of Mice and Men" is a ranch in Soledad, California.