Single reads are where one end or the whole of a fragment of DNA is sequenced. These sequences can then be joined together by finding overlapping regions in the sequence to create the full DNA sequence.
Paired-end reads are where both ends of a fragment of DNA are sequenced.
<h3>What is the role of computer in DNA sequencing?</h3>
Computers are faster
DNA sequence codes for the amino acids that form proteins, and the code had been worked out earlier.
At first, DNA sequence was read from a gel and then summarised to amino acids.
Thus, Single reads are where one end or the whole of a fragment of DNA is sequenced.
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