The correct answer is Rome, Italy. This is because although the name comes from the 19th century, the road system was used as far as 2 BC, meaning that Rome was a great empire then and there is even a saying that all roads lead to Rome. Of course it's different nowadays, but at that point in time it connected those two cities, Chang'an and Rome.
Poor growing conditions, droughts, disease, Native Americans, less profit because it costed more to transport crops.
It gave them more jobs because all the men were drafted to fight in the war.
